Hemodynamic Parameters in Predicting Time to Clinical Worsening in Pulmonary Arterial Hypertension
نویسندگان
چکیده
منابع مشابه
Predicting survival in pulmonary arterial hypertension: time to move forward.
I n the early 1980s, the National Institutes of Health (NIH) established a prospective, multicenter registry to characterise the long-term outcomes of consecutive patients with primary pulmonary hypertension (PPH) [1], which included idiopathic, heritable and anorexigens-associated pulmonary arterial hypertension (PAH) [2]. Another important objective of this registry was to determine variables...
متن کاملEarly decline in six-minute walk distance from the time of diagnosis predicts clinical worsening in pulmonary arterial hypertension.
BACKGROUND The six-minute walk distance (6MWD) is commonly used to assess pulmonary arterial hypertension (PAH). However, the role of 6MWD in predicting outcomes in PAH is controversial. Clinical worsening is being increasingly considered as a clinically meaningful end point in PAH. OBJECTIVES We aimed to investigate whether early longitudinal changes in 6MWD (Δ6MWD) in meters and percent pre...
متن کاملClinical Worsening as Composite Study End Point in Pediatric Pulmonary Arterial Hypertension.
BACKGROUND Clinical worsening (CW), an increasingly used composite end point in adult pulmonary arterial hypertension (PAH), has not yet been evaluated in pediatric PAH. This study aims to evaluate the usefulness of CW in pediatric PAH by assessing the event incidence and prognostic value of each separate component of CW and of the composite CW end point. METHODS Seventy pediatric patients wi...
متن کاملTHE EFFECTS OF CAPTOPRIL ON PULMONARY AND SYS TEMIC ARTERIAL PRESSURES IN HIGHALTITUDE PULMONARY HYPERTENSION
The purpose of this investigation was to assess the effect of captopril on both systemic (P.a) and pulmonary arterial pressures (PPA) in patients with high-altitude pulmonary hypertension (HAPH). Seventeen patients (mean age 44±6.8 years) with HAPH and mild to moderate systemic arterial hypertension were included in the study. All patients underwent right heart catheterization with measurem...
متن کاملAmbulatory Hemodynamic Monitoring in the Management of Pulmonary Arterial Hypertension
Raymond L. Benza, MD Cardiovascular Institute Allegheny General Hospital Pittsburgh, PA Background: Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling, rise in pulmonary arterial pressures, and if left untreated, right heart failure. Invasive hemodynamic assessment with right heart catheterization (RHC) has been the gold standard for the diagnosis and serial...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Heart and Lung Transplantation
سال: 2021
ISSN: 1053-2498
DOI: 10.1016/j.healun.2021.01.551